Goode suffered a hamstring injury last week. Emmanuel Acho takes his place on the gameday roster.
Wolff will miss his third consecutive game after suffering a knee injury against the Packers. Patrick Chung will start alongside Nate Allen at safety.
The Eagles once again have six wide receivers active: DeSean Jackson, Riley Cooper, Jason Avant, Jeff Maehl, Damaris Johnson and Brad Smith. Maehl suffered a concussion last week, but has been cleared to play. When Maehl was sidelined against Arizona, Smith took his snaps.
Allen Barbre (G/T) and Julian Vandervelde (center) are the backup offensive linemen.
The Eagles have four active cornerbacks: Cary Williams, Bradley Fletcher, Brandon Boykin and Roc Carmichael.
For the Lions, Reggie Bush (calf) and Calvin Johnson (knee) are active. CB Darius Slay (knee) is out.