LeSean McCoy exited in the second quarter with a right hamstring injury but did return.
The star back juked loose for a 16-yard gain late in the half. However, he went to the ground without being touched at the end of the run, then started grabbing for the back of his leg.
McCoy went to the trainers table briefly. Television cameras caught him screaming as he was being examined by team doctors. Moments later, he limped towards the locker room.
He re-entered the game in the second half.