The 27-year-old sustained a concussion late in the game against Washington. He had yet to pass the ImPACT test as of Thursday afternoon.
The Eagles’ depth in the secondary will be tested. Brandon Boykin is expected to start on the outside in Fletcher’s absence, though he could very well move into the slot in certain packages as well. Brandon Hughes, who is recovering from a fractured hand, is a logical candidate to play on the outside when Boykin does move inside.
Jordan Poyer could also factor into the equation, though the rookie appeared to struggle a bit in limited action against Washington. Safety Patrick Chung saw some time in the slot this preseason, likely in preparation for an emergency scenario.
Fletcher was targeted six times on Monday night and yielded three catches for 33 yards, per Pro Football Focus. He finished with four tackles.
Dennis Kelly (back) has also been ruled out for the Chargers game. He was a limited participant in practice this week and appears to be recovering well from back surgery. He is set to meet with his doctor on Sunday and expects to be cleared for all football activity at that time. The tackle said that he is targeting the Denver game for his return.
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